LIFE CYCLE OF AMELOBLAST PDF

Ameloblasts are cells present only during tooth development that deposit tooth enamel , which is the hard outermost layer of the tooth forming the surface of the crown. Each ameloblast is a columnar cell approximately 4 micrometers in diameter, 40 micrometers in length and is hexagonal in cross section. The secretory end of the ameloblast ends in a six-sided pyramid-like projection known as the Tomes' process. The angulation of the Tomes' process is significant in the orientation of enamel rods , the basic unit of tooth enamel.

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Life cycle of ameloblasts Morphogenic stage: Organising stage: Formative stage: Maturative stage: Protective stage: Desmolytic stage:. Morphogenic phase during the morphogenic stage shape of the crown is determined cells of the inner enamel epithelium are cuboidal or low columnar with large centrally located nuclei and poorly developed Golgi separated from the dental papilla by a basement membrane IEE cells influence dental papilla cells to differentiate into odontoblasts.

Organising stage Ameloblasts elongate. Almost become double in length Nuclei shift toward the stratum intermedium Reversal of functional polarity. Cell becomes polarized with most of the organelles distal to the nucleus at the distal end of the cell extensions form called Tomes processes - against which enamel forms Basement membrane fragments by the cytoplasmic projections of the ameloblasts during the formation of predentin this allows contact between the pre-ameloblasts and pre-odontoblasts Reversal of nutritional supply.

Secretory Stage cells acquire intense synthetic and secretory activity enamel proteins are translated by the RER, modified by the Golgi and packaged into secretory granules migrate to the distal Tomes processes. Maturative stage Ameloblast bring about changes in the physiochemical properties of the enamel actually because the pre-existing HA crystals of the enamel grow in width and thickness and NOT because new crystals are made made up of a transitional phase and the maturation proper phase transitional phase after the full thickness of the enamel has formed the ABs undergo significant morphological changes that prepares them for the maturation of the enamel reduction of AB height and a decrease in their volume and organelle content.

Protective stage After accomplishing of amelogenesis, the ameloblasts secrete or leave structure less material on enamel surface, known as primary enamel cuticle. The dental organ epithelium becomes reduced in thickness reduced enamel epithelium and functions as a protection against contact with connective tissue to inhibit cementum deposition or enamel resorption.

In this stage the composition of Enamel can be modified. Desmolytic stage The reduced enamel epithelium induce atrophy of the mesoderm which separate it from the oral epithelium. It leads to eruption. REE releases proteolytic enzymes which cause breakdown of collagen fibers As tooth approaches oral epithelium both epithelium and REE proliferated They fuse to each other forming epithelial plug This degenerated to form a pathway for eruption.

Formation of Enamel Enamel formation takes place in two steps Formation of organic matrix Mineralisation Early incomplete mineralization Maturation. Learn more about Scribd Membership Home. Much more than documents. Discover everything Scribd has to offer, including books and audiobooks from major publishers.

Start Free Trial Cancel anytime. Life Cycle of Ameloblast. Uploaded by imi4. Document Information click to expand document information Description: Life cycle of ameloblasts before enamel formation. Date uploaded May 12, Did you find this document useful? Is this content inappropriate?

Report this Document. Description: Life cycle of ameloblasts before enamel formation. Flag for Inappropriate Content. Download Now. Related titles. Carousel Previous Carousel Next. Jump to Page. Search inside document. Almost become double in length Nuclei shift toward the stratum intermedium Reversal of functional polarity Cell becomes polarized with most of the organelles distal to the nucleus at the distal end of the cell extensions form called Tomes processes - against which enamel forms Basement membrane fragments by the cytoplasmic projections of the ameloblasts during the formation of predentin this allows contact between the pre-ameloblasts and pre-odontoblasts Reversal of nutritional supply.

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Ameloblast

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LIFE CYCLE OF AMELOBLAST

Life cycle of ameloblasts Morphogenic stage: Organising stage: Formative stage: Maturative stage: Protective stage: Desmolytic stage:. Morphogenic phase during the morphogenic stage shape of the crown is determined cells of the inner enamel epithelium are cuboidal or low columnar with large centrally located nuclei and poorly developed Golgi separated from the dental papilla by a basement membrane IEE cells influence dental papilla cells to differentiate into odontoblasts. Organising stage Ameloblasts elongate. Almost become double in length Nuclei shift toward the stratum intermedium Reversal of functional polarity. Cell becomes polarized with most of the organelles distal to the nucleus at the distal end of the cell extensions form called Tomes processes - against which enamel forms Basement membrane fragments by the cytoplasmic projections of the ameloblasts during the formation of predentin this allows contact between the pre-ameloblasts and pre-odontoblasts Reversal of nutritional supply. Secretory Stage cells acquire intense synthetic and secretory activity enamel proteins are translated by the RER, modified by the Golgi and packaged into secretory granules migrate to the distal Tomes processes.

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Life Cycle of Ameloblast

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