Heliopsis longipes S. Blake Asteraceae: Heliantheae chilcuague is used in Mexican traditional medicine against parasites and to alleviate tooth and muscle pains. Its biocide effect has already been experimentally demonstrated; however, its analgesic action and its action on the nervous system NS have not been investigated yet. The objectives of this study were to evaluate the analgesic action of affinin and the H.

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Heliopsis longipes is an herbaceous plant found in Mexico. Heliopsis longipes is traditionally used for its analgesic and anesthetic properties. Plant extracts may represent a therapeutic advantage for the clinical treatment of pain. Therefore, the main objective of this study was to determine the possible antihyperalgesic effect produced by the Heliopsis longipes ethanolic extract HLEE in the Hargreaves model of thermal hyperalgesia in the mouse.

HLEE was administrated systemically to mice and the antihyperalgesic effect was evaluated using the thermal hyperalgesia test. Previously, it was reported that Heliopsis longipes extract was able to release GABA in mice temporal cortex slices.

Therefore, it is likely that the antihyperalgesic effect observed in our study could result from GABA liberation and its inhibition of excessive excitation of nociceptive circuits in the thalamus and cortex evoked by tissue injury. Our results suggest that HLEE may represent a therapeutic advantage for the clinical treatment of inflammatory pain. This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features!

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Acosta-Madrid II, et al. Epub Feb 5. PMID: Antinociceptive, genotoxic and histopathological study of Heliopsis longipes S.

Blake in mice. J Ethnopharmacol. Epub May 8. Anti-inflammatory effects of ethanolic extract and alkamides-derived from Heliopsis longipes roots. Epub May 9. Antinociceptive effect of Heliopsis longipes extract and affinin in mice. Planta Med. Epub Nov Final report on the safety assessment of capsicum annuum extract, capsicum annuum fruit extract, capsicum annuum resin, capsicum annuum fruit powder, capsicum frutescens fruit, capsicum frutescens fruit extract, capsicum frutescens resin, and capsaicin.

Int J Toxicol. PMID: Review. Show more similar articles See all similar articles. Castro-Ruiz JE, et al. Int J Mol Sci. MeSH terms Animals Actions. Male Actions. Mice Actions. Substances Plant Extracts Actions. Copy Download.


Analgesic Activity of Heliopsis Longipes and Its Effect on the Nervous System

Heliopsis longipes is a rare species of flowering plant in the sunflower family. The root is chewed to numb the tongue and relieve pain in the teeth and throat. It has antibiotic properties so it is traditionally used against throat infection, pharyngitis, tonsillitis, laryngitis, esophagitis, gingivitis and other infections even on the skin , it is also recognized as a powerful antifungal traditionally used against athlete's foot, onychomycosis, dandruff and candidiasis or milkweed , is analgesic [4] , antiseptic, anesthetic It is traditionally used in the painful dentition presented by babies helping to immediately eliminate the discomfort caused by the appearance of the first teeth , and has excellent results when applied after from the bite of an insect such as a bee, wasp or spider. It is also used as a condiment in foods and alcoholic beverages.


Antihyperalgesia Induced by Heliopsis Longipes Extract






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