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However, some uncertainties still exist in the literature about their morphological definition. The aim of this paper is to discuss this topic and to suggest a univocal definition of acanthocytes as erythrocytes with the shape of a ring with one or more protrusions.. In , Fairley and Birch described dysmorphic red blood cells and proposed their use to distinguish glomerular from non-glomerular haematuria. However, in spite of this, a univocal definition of acanthocyte is still missing. The aims of this paper are 1.