COLY MYCIN M PDF

Among the new antibiotics investigated clinically in Houston during the past two years, colistin Coly-Mycin has been one of the most promising. This antibiotic was isolated in Japan by Yosuo Koyama in from culture filtrates of Bacillus colistinus, a bacterium closely related to Bacillus polymyxa, the source of the polymyxins. Its pharmacology has been studied in Japan, Italy, France, and, more recently, this country. A summary of the findings of these studies indicates that the chemical, pharmacological, and antimicrobial activity of colistin is closely related to the polymyxins, Clinically, however, colistin causes fewer undesirable side-effects. Colistin is a complex polypeptide, with an empirical formula of C 45 H 85 O 10 N 13 and a molecular weight of Its acid salts are stable in solution even for very long periods; alkaline salts are less stable.

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Please call the pharmacy to inquire about store hours or delivery service as they may have changed. This medication contains an antibiotic. Typically, it is used to treat infections. It requires several days to take effect. This drug can, on occasion, be administered in a hospital or clinic setting by a doctor or a nurse, but can also be used at home. If you are taking this drug at home, make sure that the health care facility overseeing your treatment has provided you with all the necessary information regarding its administration.

It is very important that you comply with the directions for use to fully benefit from the effects of this drug and to limit any adverse reactions. In addition to its desired action, this medication may cause some side effects, notably: it may cause dizziness -- use caution when getting up from a lying or sitting position; it may cause numbness and a decreased sensitivity to touch; it may cause stinging or itching; it may cause indigestion; it may cause a tingling feeling.

Each person may react differently to a treatment. If you think this medication may be causing side effects including those described here, or others , talk to your doctor or pharmacist. He or she can help you to determine whether or not the medication is the source of the problem.

Respect the provided storage instructions for this product. If you have any questions, speak to the health care professionals who are overseeing your treatment. This information handout only provides an overview of your treatment. Given the complex nature of your treatment, you will receive information that is much more comprehensive and that deals specifically with your needs. Make sure that you have all the relevant information regarding your medication.

It is important to tell the health professionals you consult: if you have a history of any other medical condition, whether you smoke and for women, if you are or want to become pregnant or breastfeeding; if you have allergies to any medications or any other allergies e.

This document contains useful information for those taking this medication. It is not intended, in any way, to replace the advice of a trained health professional. For more information, consult the manufacturer's literature, where you will find additional information about uncommon side effects as well as contraindications associated with this product.

This content is for information purposes only and does not in any manner whatsoever replace the opinion or advice of your health care professional. Always consult a health care professional before making a decision about your medication or treatment.

How to use this medication This drug can, on occasion, be administered in a hospital or clinic setting by a doctor or a nurse, but can also be used at home.

Possible side effects In addition to its desired action, this medication may cause some side effects, notably: it may cause dizziness -- use caution when getting up from a lying or sitting position; it may cause numbness and a decreased sensitivity to touch; it may cause stinging or itching; it may cause indigestion; it may cause a tingling feeling.

Storage information Respect the provided storage instructions for this product. Additional information This information handout only provides an overview of your treatment. General information It is important to tell the health professionals you consult: if you have a history of any other medical condition, whether you smoke and for women, if you are or want to become pregnant or breastfeeding; if you have allergies to any medications or any other allergies e.

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Coly-Mycin® M Colistimethate 150 mg Parenteral Injection Single Dose Vial 10 mL

Medically reviewed by Drugs. Last updated on Mar 23, Antibacterial; prodrug of colistin a polymyxin antibiotic structurally and pharmacologically related to polymyxin B. Treatment of acute or chronic infections caused by certain susceptible gram-negative bacteria e. Used only when the causative agent is susceptible and other more effective and less toxic anti-infectives are contraindicated or ineffective.

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